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Collagen peptide extraction process and application prospects help you plan ahead in the health industry!

June 11, 2024

The National Food Safety Standard - Collagen Peptides (GB 31645-2018) stipulates that collagen peptides are products with a relative molecular weight of less than 10000 Da, produced from fresh animal tissues (including skin, bone, tendons, tendons, scales, etc.) through extraction, hydrolysis, and refinement.

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What is collagen peptide?

Collagen is the most abundant protein in the human body, accounting for approximately 30-40% of the total protein content. Collagen is an important functional polysaccharide protein that is widely distributed in soft and hard connective tissues of living organisms. Along with elastin and keratin, it forms the extracellular skeleton, also known as the "scaffold of life". Collagen peptide is a natural, biologically active protein and a food ingredient obtained through enzymatic hydrolysis of collagen. Unlike ordinary collagen, collagen peptides are more easily absorbed and utilized by the human body, which can effectively increase the content of collagen.

Collagen peptides are widely used in various fields:

In the field of health products: Collagen peptides can be finely processed and made into oral or topical health products, providing a variety of nutrients and physiological active substances to promote physical health and care.
In the field of cosmetics: Collagen peptides are widely used in skincare products, which can help improve skin elasticity and glossiness, reduce the appearance of wrinkles and fine lines.
In the medical field, collagen peptides can be used to treat osteoporosis and arthritis, promote the growth and differentiation of bone cells, increase bone density, and protect and repair joint cartilage, reducing joint pain and inflammation. Collagen peptides also have many physiological regulatory functions, including antioxidant, anti-tumor, blood pressure lowering, cholesterol lowering, weight loss and blood lipid lowering, regulating the human immune system, and promoting the absorption of minerals such as calcium ions.
In recent years, the popularity of collagen peptides has been increasing year by year. Through Google search, it was found that the popularity of protein raw materials in Google Trends has shown a significant upward trend in collagen peptides. From a global market perspective, the United States, North America, Europe, and South America are more focused on comprehensive health, exercise nutrition, and bone and joint health, which is also the trend in China's future market.
Data shows that in 2013, only 7% of sports nutrition products added collagen peptides, which increased to 41% in 2018. The popularity trend of collagen peptides in sports nutrition products is increasing, and their combination with sports nutrition products will become increasingly close.
Extraction process of collagen peptide

At present, the main methods for preparing collagen peptides include chemical methods and enzymatic hydrolysis. Chemical method is the use of chemical reagents such as acids and bases to promote collagen hydrolysis and produce small molecule peptides. The enzyme law uses enzyme preparations to cleave collagen and break it down into small peptide molecules. Chemical reactions are intense, difficult to control, and there may be residual organic solvents during the extraction process. Enzymatic hydrolysis has the advantages of mild reaction conditions, low cost, high safety, and fewer by-products, making it the most commonly used method for the preparation of collagen peptides.

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01

Raw material selection: The main raw materials include fish skin, scales, pig/beef bones, etc., which are required to come from fresh, safe, and pollution-free sources.

02

Pre treatment: mainly by controlling temperature, acid, alkali, and salt to treat degreasing, decalcification, and removing impurities, to improve the purity of collagen and ensure the purity of collagen peptides.

03

Enzymatic hydrolysis: Based on the quality parameter requirements of the target collagen peptide, optimize and screen the combination and dosage of composite enzymes, control the hydrolysis temperature, pH value, and hydrolysis time for efficient enzymatic hydrolysis, and after reaching the hydrolysis endpoint, kill the enzyme by heating or adjusting the pH value.

04

Refined separation: Selective adsorption decolorization, removal of fishy and astringent flavors through activated carbon or other adsorbents, removal of impurities and adsorbents through coarse filtration, centrifugal separation, and plate and frame filtration, membrane separation, removal of pigments, odors, salts, as well as macromolecular proteins and peptides, and control of product molecular weight.

05

Concentration: Concentrate by membrane or evaporation until the concentration of collagen peptide solution reaches 20% to 45%, saving energy consumption and improving efficiency for subsequent drying.

06

Sterilization and drying section: the concentrated materials are sterilized by UHT, and collagen peptide powder or particles are obtained through the spray drying tower combined with the granulator to control the moisture, particle size and fluidity of the product.

07

Packaging finished products: After passing the finished product inspection, design packaging as needed, and store them in the warehouse after filling and packaging.


Shaanxi Huike Botanical Development Co., Ltd. a integrated enterprise which is focus on natural products, Plant extract related products and services.We mainly focus on pharmaceutical, functional food, Freeze-dried powder,Natural Pigment,Homology of medicine and food,beverages and other business services.
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2024-06-11


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