Common medicinal and food homologous ingredients that help improve sleep

November 30, 2023

According to relevant regulations, sour jujube kernels, big dates, lilies, gardenia, Poria cocos, bergamot, etc. can be used as both food and medicine, thus possessing the characteristics of medicinal and edible homology. Research has shown that all the above-mentioned traditional Chinese medicines have certain sedative and hypnotic effects.

Sour jujube kernel

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According to literature reports, the total saponins, total alkaloids, and unsaturated fatty acids in sour jujube kernel oil all have certain sedative and hypnotic effects, with sour jujube kernel saponins being the strongest. Research has shown that spinosol and jujube seed saponin A are the main components of jujube seed's sedative and hypnotic activity, and their mechanisms of action are related to antagonizing the postsynaptic 5-HT1A receptor and increasing the expression of GABAA receptor.

Jujube

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Jujube contains alkaloids (such as matrine and N-demethyl lotus leaf alkaloids), triterpenoid acids (such as oleanolic acid and hawthorn acid), glycosides (such as non prickly jujube benzyl glycoside I and non prickly jujube benzyl glycoside II), saponins (such as jujube saponins and sour jujube saponins), and other components. Research has shown that the alkaloids, flavonoids, and glycosides in jujube have a certain sedative effect on sleep.

Lily

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Lily contains active ingredients such as lily polysaccharides and lily saponins. According to literature reports, fresh lilies have significant sedative and hypnotic effects on mice; The total saponins of lilies have a regulatory effect on the 5-hydroxytryptamine system function in mice.

Gardenia jasminoides

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The extract of gardenia contains components such as gardenia yellow pigment, gardenoside, gardenia lactone, and gardenia flavonoids. Research has shown that gardenia yellow pigment has a certain sedative and hypnotic effect.

Poria cocos

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The main effective ingredients of Poria cocos are Poria cocos polysaccharides and triterpenoids, and Poria cocos acid is a unique tetracyclic triterpenoid compound of Poria cocos. According to literature reports, the decoction of Poria cocos, carboxymethyl Poria cocos polysaccharides in Poria cocos, total triterpenes in Poria cocos, and Poria cocos acid all have sedative and hypnotic effects. The hypnotic effect of Poria cocos acid is related to its regulation of the brain γ- The expression level of aminobutyric acid A receptor is related.

Buddha's hand

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Buddha's hand contains volatile oil (such as β- Caryophyllene α- Caryophyllene, flavonoids, polysaccharides, polyphenols, amino acids, and trace elements. Research has shown that bergamot has a sedative effect on mice. The antidepressant effect of bergamot volatile oil shows a significant dose-related characteristic, which is related to its regulation of central function and improvement of sleep.

Perilla frutescens

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Perilla can be used as medicine in three parts: leaves, stems, and fruits. Perilla seeds mainly contain unsaturated fatty acids and proteins; Perilla leaves contain volatile oil, mainly composed of perilla aldehyde, limonene β- Dingxiangene, etc; Perilla stems contain components such as perillaldehyde and isoproterenone. According to literature reports, perilla water extract has good sedative and hypnotic effects on mice.

Black pepper

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Black pepper contains effective ingredients such as piperine, piperine, volatile oil, piperacillin, and various piperacillins. Research has shown that pepper has significant sedative and hypnotic effects.

Nutmeg

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Seed kernels contain fatty oils (such as triglycerides and oleic acid glycerides) and volatile oils (such as α- Pinene and D-camphor, as well as components such as nutmeg ether. According to literature reports, the volatile oil of nutmeg has a certain sedative and hypnotic effect.

Coix seed

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Coix seed contains various components such as lipids, polysaccharides, lignans, phenols, and adenosine. The main components in Coix seed oil are oleic acid and linoleic acid. Research has shown that Coix seed extract can reduce spontaneous activity in mice, increase amplitude and slow down frequency of brain waves in rabbits, and exhibit a certain sedative effect.

Licorice

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Licorice mainly contains glycyrrhizin, as well as flavonoids such as glycyrrhizin and glycyrrhetinic acid. According to literature reports, intraperitoneal injection of licorice extract in mice can produce significant sedative and hypnotic effects.

Longan meat

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The methanol extract of longan pseudoderm can enhance the hypnotic effect of pentobarbital; Longan meat extract has anti stress and anti anxiety effects, and its effective ingredients are adenosine, adenine, and uridine.

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2023-12-28

Shaanxi Huike Botanical Development Co., Ltd.

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