The latest research progress on silkworm pupa peptides! 6 "hardcore" functions to protect human health

June 25, 2024

When it comes to silkworm pupae, people's attitudes vary greatly. Some people think it is a delicious food, while others completely cannot accept it. In fact, the consumption of silkworm pupae has a history of over 1400 years in China. It is not only a food ingredient, but also considered a precious medicinal herb, which is recorded in medical classics such as the Compendium of Materia Medica and the General Records of Shengji.

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In recent years, with in-depth research on silkworm pupae, scientists have discovered that bioactive peptides extracted from silkworm pupae have the characteristics of small molecules and easy absorption, which can effectively improve human health and prevent the occurrence of various diseases.
The nutritional value of silkworm pupae
Silkworm pupae are abundant in resources in China, with a protein content of over 60% and containing 18 types of amino acids. Silkworm pupa protein is a full valent protein with a complete variety of amino acids, good balance of essential amino acids, appropriate ratio, and compliance with FAO/WHO standards. It is an ideal high-quality protein and rich in nutrients such as riboflavin, niacin, zinc, iron, and copper.

Six health benefits of silkworm pupa peptides

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Silkworm pupa peptides can be quickly absorbed and utilized by the human body, quickly replenishing high-quality proteins. At the same time, they also have various physiological regulatory functions, repairing body damage and improving physiological functions from multiple aspects.

1. Antioxidant

Silkworm pupa peptides have good DPPH scavenging ability, reducing power, superoxide anion free radical scavenging ability, hydroxyl scavenging ability, and good antioxidant stability under certain conditions, making them widely applicable in the fields of medicine, cosmetics, and food.

2. Stable blood pressure

Angiotensin converting enzyme (ACE) can promote the conversion of angiotensin I to angiotensin II, stimulate vasoconstriction, and cause an increase in blood pressure. Therefore, inhibiting ACE activity has a positive effect on lowering blood pressure.
In a national invention patent, researchers have prepared silkworm pupa peptides with excellent ACE inhibitory activity and good antioxidant function through enzymatic hydrolysis, which can be widely used in the manufacturing of special and nutritional foods.

3. Enhance immune function

Research has shown that silkworm pupa peptides can increase the weight index of thymus and spleen in normal and immunocompromised mice, as well as the peripheral blood white blood cell count in immunocompromised mice. They promote the proliferation of T and B lymphocytes in the spleen of normal and immunocompromised mice, and have the function of enhancing cellular immunity.

4. Anti tumor

Silkworm pupa peptide has cycle specificity on lung cancer and kidney cancer cells, can cause DNA damage to cells, has inhibitory effects on tumor cells from different tissue sources, and has certain anti-tumor activity.

5. Regulating blood sugar

The animal experiment showed that the silkworm pupa peptide could significantly reduce the fasting blood glucose and the content of glycosylated serum protein in diabetes mice. The heart index, kidney index and liver index were improved to a certain extent, which had a certain hypoglycemic effect.

6. Anti fatigue

The silkworm pupa peptide group can significantly increase the content of liver glycogen and muscle glycogen in mice, reduce the content of serum urea nitrogen during exercise, and reduce the content of blood lactate during exercise, with good anti fatigue effect.

Silkworm pupa peptide, as a foodborne bioactive peptide derived from insects, has a dual function of nutritional supplementation and physiological regulation. It is believed that with the continuous deepening of research, more unique effects of it will be discovered, helping us better delay the aging process and maintain a healthy state.

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2024-06-25

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